L-Glutamine is the most abundant amino acid in the body, critically important for the immune system, gut health, and muscle recovery after intense training.

L-Glutamine – the most abundant amino acid in the human body, accounting for ~60% of all free amino acids in muscle. It is a conditionally essential amino acid — the body produces it, but during intense training, injury, or illness, demand exceeds production.
Mechanism of action: glutamine is the main energy source for enterocytes (intestinal cells) and immune cells (lymphocytes, macrophages). Intense training reduces glutamine levels in the blood, weakening immunity.
There are various forms of this supplement on the market, and not all of them are equally effective. Here are the main criteria to consider when choosing:
Correct dosage is critically important for achieving the desired results. Below are scientifically based dosage recommendations:
| Purpose | Recommended Dose | Notes | Source |
|---|---|---|---|
| Immune Support | 5-10 g/d. | After intense training. Prophylactically. | overview |
| Gut Health | 5-10 g 2-3x/d. | In cases of intestinal permeability (leaky gut). | overview |
| For muscle recovery | 5-10 g after training | With protein or carbohydrates. | overview |
Below are the most significant peer-reviewed scientific studies supporting the effectiveness of this supplement. Each study was published in peer-reviewed literature.
📌 Note: Study results may vary depending on the population, dosage and study duration. Always evaluate scientific evidence critically.
This supplement may interact with other supplements — synergistically enhance the effect or compete for absorption. Proper combination can significantly increase overall effectiveness and reduce the risk of side effects:
Although most people tolerate this supplement well, especially when taken at recommended doses, it is important to know the possible side effects, contraindications and interactions with medications:
Below are interesting facts and statistics related to this supplement, based on scientific research and market data:
Based on the latest scientific research and practical experience, we provide key tips for achieving the best results when taking this supplement:
We answer the most frequently asked questions about this supplement. If you did not find the answer to your question, we recommend consulting a sports nutrition specialist:
The evidence is mixed. Glutamine has a greater effect on immunity and gut health than on direct muscle synthesis.
After training or before bed. The most important thing is regularity, especially during periods of intense training.
For beginners, we recommend following this simple but effective plan to achieve the best results and avoid unnecessary side effects:
You can purchase this and other high-quality supplements staystrong.lt in the online store. Every product is carefully selected, meets the highest quality standards, and has all the necessary certificates.
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All products are carefully selected in cooperation with only reliable manufacturers. Every product undergoes quality control. Our team constantly follows the latest scientific research and market trends in order to offer only the most effective solutions.
Glutamine is the most abundant amino acid in the blood and muscles, so its levels are adjusted with supplements only when there is a true deficiency. Textbooks emphasize that the body synthesizes glutamine itself, so for a healthy person the benefit of supplementation for athletic performance has not been proven.
Greater attention is given to glutamine in clinical situations — after major trauma, burns, or severe illness, when the body is under stress and glutamine demand increases. This is clinical, not the field of sports nutrition.
Practical: instead of glutamine supplementation, it is better to ensure adequate total protein intake — it also covers glutamine needs.
Source: NSCA guide “Guide to Sport and Exercise Nutrition” (p. 42); Webb G. P., “Dietary Supplements and Functional Foods” (Blackwell, 2006).