Testosterone, Cortisol, T3, T4, GH, Insulin: Which Hormones to Test and How to Optimize Them

Hormones control practically EVERYTHING: muscle growth, fat burning, energy levels, recovery, sleep, mood and libido. A balanced hormonal system = optimal athletic performance. An imbalanced one = efforts go to waste.
Testosterone, growth hormone (GH), IGF-1 — responsible for muscle protein synthesis, recovery, strength.
Cortisol, glucagon — break down tissues for energy. Essential, but too much destroys muscle.
T3, T4 (thyroid), insulin — regulate metabolic rate, carbohydrate and fat utilization.
Leptin, ghrelin — control appetite. During dieting, they are the first to become disrupted.
| Hormone | Function for Athlete | Optimal Level | When to Test | How to Optimize |
|---|---|---|---|---|
| 🧔 Testosterone (Total) | Muscle growth, strength, libido | 500-900 ng/dL (M); 30-70 (F) | Morning, fasting | Sleep, Zn, Mg, fats (≥20% kcal) |
| 🧔 Free Testosterone | Biologically active T | 10-20 ng/dL (M) | Along with total | SHBG reduction (boron, magnesium) |
| ⚡ Cortisol (Morning) | Stress response, energy | 10-20 μg/dL (morning) | 7-9 a.m., fasting | Sleep, adaptogens (ashwagandha) |
| 🔄 T3 (Free) | Metabolic rate | 3.5-4.5 pmol/L | Fasting | Carbohydrates, selenium, zinc |
| 🔄 T4 (Free) | Thyroid reserve | 12-22 pmol/L | Fasting | Iodine, selenium, avoid deficiency |
| 🏋️ IGF-1 | Growth factor activity | 150-350 ng/mL | Fasting | Protein (≥1.8 g/kg), sleep |
| 🍬 Insulin (Fasting) | Carbohydrate metabolism | 2-6 μIU/mL | Fasting (8-12 h) | Reduce refined carbohydrates |
| 🧠 Leptin | Satiety signal | Individual (monitor trend) | Morning | Refeed days, sufficient calories |
Testosterone is the most important anabolic hormone. Sport can BOTH INCREASE AND DECREASE it — depending on the load:
Cortisol is not "bad" — it is necessary for energy. The problem is CHRONIC high cortisol, which breaks down muscle, stores belly fat, and weakens immunity.
Signs that cortisol is too high:
Choose quality supplements to achieve your goals:
Athletes have unique physiological needs that make this topic even more relevant:
Athletes of different levels require a different approach:
Focus on the basics: balanced nutrition, sufficient protein intake, vegetables at every meal. Do not rush with complex strategies — first learn the basic habits.
Start experimenting with meal timing and macro periodization. Monitor how your body responds to different carbohydrate amounts before/after workouts.
Individualize everything: blood tests every 3-6 months, DEXA scans, sports dietitian consultations. Small details can provide a decisive 1-2% advantage.
In addition to the main supplements, these products can help you achieve better results: