A comprehensive guide to magnesium forms: bisglycinate for sleep, citrate for digestion, threonate for the brain, malate for energy. Which form is best for your goals?

Magnesium is involved in more than 300 enzymatic reactions in the body. It is especially important for athletes: it regulates muscle contraction and relaxation, supports nervous system function, and participates in energy (ATP) production and protein synthesis. Magnesium deficiency is one of the most common reasons why athletes experience cramps, fatigue and poor sleep.
| Magnesium Form | Elemental Mg % | Bioavailability | Main Benefit | Side Effects | Rating |
|---|---|---|---|---|---|
| Bisglycinate | ~10-14% | Very high | Sleep, muscle relaxation, stress | Minimal | ★★★★★ |
| Citrate | ~11-16% | High | Digestion, energy | Diarrhea (at high doses) | ★★★★ |
| Threonate | ~8% | High (crosses BBB) | Brain, concentration, memory | Minimal | ★★★★ (specific) |
| Malate | ~11-15% | High | Energy, fibromyalgia, chronic fatigue | Minimal | ★★★★ |
| Chloride | ~12-25% | Medium-High | Rapid replenishment, skin benefits | Diarrhea | ★★★ |
| Oxide | ~60% | Very low (4%) | Laxative effect | Diarrhea, abdominal pain | ★ (not recommended) |
Magnesium Bisglycinate — glycine acts as a calming neurotransmitter, improves sleep quality and reduces time to fall asleep. Recommended dose: 200-400 mg before bed.
Magnesium citrate or bisglycinate — both effectively reduce muscle spasms. Citrate is absorbed slightly faster but may cause diarrhea in sensitive individuals.
Magnesium threonate — the only form that effectively crosses the blood-brain barrier. There is evidence of better memory, learning and cognitive function. But it is the most expensive form.
Magnesium malate — malic acid is involved in the Krebs cycle (ATP production). It is especially suitable for those suffering from chronic fatigue syndrome or fibromyalgia.
Magnesium supplements differ in that, what magnesium is bound to — both absorption and tolerability depend on this. In textbooks, magnesium is discussed as a mineral whose requirement may increase during exercise due to losses through sweat.
Practical difference: some forms are better absorbed but may weaken digestion, others are tolerated better but have a lower amount of elemental magnesium. Therefore, on the label it is important to look not at the total compound mass, but at the elemental magnesium content.
Most importantly: first, it is worth assessing your diet — nuts, seeds, whole-grain products and leafy vegetables are natural sources of magnesium.
Source: “The Complete Guide to Food for Sports Performance” (p. 84); NSCA guide “Guide to Sport and Exercise Nutrition”.