What Is NAC?
N-acetylcysteine (NAC) is the acetylated form of the amino acid cysteine. NAC is the main precursor of glutathione — the body's most powerful antioxidant. Glutathione is essential for detoxification in the liver, protection against oxidative stress, immune system function, and cellular protection. NAC also acts as a mucolytic — it thins mucus in the lungs.
🧪 What the Science Says
🧹 Liver Detoxification
NAC is the standard antidote for paracetamol poisoning — it restores glutathione stores in the liver and protects against liver failure. It is used in hospitals worldwide.
🫁 Lung Health
NAC reduces mucus viscosity and improves lung function in COPD and bronchitis. For athletes, it may help with respiratory tract inflammation.
🏋️ Sports Recovery
NAC (1.2 g/d) reduced oxidative stress markers after intense training and accelerated recovery. However, continuous high-dose use may suppress the positive adaptation to oxidative stress.
🧠 Mental Health
There is new data on NAC's potential in treating depression, bipolar disorder, OCD, and addictions. It acts through modulation of the glutamate system in the brain.
📋 Dosage Recommendations
- For general antioxidant protection: 600-1200 mg per day, divided into 2 doses
- For detoxification: 1200-2400 mg per day for a short period
- For lung health: 600 mg 3 times per day
- For sports: 600-1200 mg after training (not before — may reduce adaptation)
- With Food or Without? Better with food to avoid stomach irritation
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❓ Frequently Asked Questions
Can NAC Harm Sports Performance?
Paradoxically, yes — if used continuously in high doses. Oxidative stress after training is a signal that promotes adaptation. Too many antioxidants can suppress this signal. Use NAC periodically, not daily.
Does NAC Have a Smell?
Yes, NAC has a characteristic sulfur smell (similar to rotten eggs). This is normal and indicates that the product is pure. The smell is stronger in powder and weaker in capsules.