Learn how to protect your immune system during intense exercise. Vitamins, minerals, adaptogens and nutrition strategies for strong immunity all year round.

Moderate physical activity strengthens immunity, but intense training (especially long endurance training) temporarily weakens it. This phenomenon is called the "open window" effect — after intense training, the immune system is weakened for 3–72 hours.
| # | Supplement | Mechanism of Action | Dose | Effectiveness |
|---|---|---|---|---|
| 1 | Vitamin C | Antioxidant, stimulates white blood cell production | 500–2000 mg/d | Proven |
| 2 | Vitamin D3 | Activates T cells, reduces inflammation | 2000–4000 IU/d | Proven |
| 3 | Zinc | Essential for immune cell production and function | 15–30 mg/d | Proven |
| 4 | Echinacea | Increases phagocytosis, reduces cold duration | 300–500 mg extract | Proven |
| 5 | Quercetin | Strong antioxidant, reduces histamine release | 500–1000 mg/d | Promising |
| 6 | Probiotics | Improves gut microbiota (70% of immunity is in the gut) | 10–50 billion CFU/day | Proven |
| 7 | Garlic (allicin) | Antimicrobial, antiviral effect | 600–1200 mg extract | Promising |
| 8 | Ginseng | Adaptogen, increases stress resistance | 200–400 mg extract | Promising |
| 9 | Ashwagandha | Reduces cortisol, improves resistance to infections | 300–600 mg/d | Promising |
| 10 | Omega-3 (DHR+EPR) | Reduces chronic inflammation, improves immune response | 1–3 g/d | Proven |
Colorful vegetables and fruits: broccoli, peppers, berries, citrus fruits. Antioxidants neutralize free radicals after training.
Fermented products: kefir, yogurt, sauerkraut, kimchi. Probiotics and prebiotics (onions, garlic, Jerusalem artichokes).
Garlic, ginger, turmeric, honey. They have natural antimicrobial properties and help fight infections.
Sufficient water intake is essential for the lymphatic system, which transports immune cells throughout the body.
Sleep is one of the most important but often overlooked factors in strengthening immunity. During sleep, the body produces cytokines — proteins that fight infections and inflammation.
Recommendations for athletes: 7–9 hours of quality sleep. Additionally, 30–60 min after intense training. Magnesium before sleep can improve sleep quality.
Adaptogens are natural substances that help the body adapt to stress (physical, psychological, environmental). They regulate cortisol levels, improve energy and strengthen immunity.
These supplements will help strengthen the immune system and maintain health:
The strategy for strengthening immunity should vary depending on the time of year.
The greatest risk — flu, colds. Priority: Vit. D3 (4000 IU), zinc, echinacea, garlic. Less sun = more vit. D.
Allergies, the body's transition. Priority: quercetin, vit. C, probiotics. Gradually increase the volume of outdoor training.
Risk of dehydration, heat stroke. Priority: electrolytes, vit. C, antioxidants. Protect the skin from the sun (vit. E as well).
Preparation for winter, strengthening immunity. Priority: building Vit. D3 stores, zinc, probiotics, adaptogens.
Athletes are recommended to get a flu vaccination annually. After vaccination, it is recommended not to do intense training for 24–48 hours — the body needs energy for antibody production. Light activity (walking) is allowed and may even improve the immune response.
Here are a few simple and tasty smoothies you can make yourself to strengthen immunity:
Traditional herbs that may help strengthen immunity:
In Lithuania, due to its geographical location, vitamin D deficiency is especially widespread — the population has insufficient vitamin D levels during the winter months. People who exercise are no exception — when vitamin D is lacking, not only immunity but also muscle strength declines. Recommendation: take 2000–4000 IU of vitamin D3 daily from October to April.
The relationship between training load and immunity is described in textbooks as two-sided: moderate physical activity is associated with more favorable immune system indicators, while very high long-term loads — with an increased risk of upper respiratory tract infections in the days after competition.
The most important practical conclusion: immunity is more determined by sleep, nutrition, and load management, not an individual supplement. Therefore, it is worth addressing these three things first.
Source: NSCA guide “Guide to Sport and Exercise Nutrition” (p. 48); Webb G. P., “Dietary Supplements and Functional Foods” (Blackwell, 2006).